Rethinking the Immune Response as Metabolic Process

Immune responses are energetically expensive. Not surprisingly, secreted metabolites are increasingly emerging as important factors in immune cell maturation and activation, as this new review by Sidonia Fagarasan et al. demonstrates.

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Spermidine to the Rescue?

Spermidine, a polyamine compound found in ribosomes and living tissues and originally isolated from semen, can enhance cancer immunotherapy blocking the PD-1 pathway by reversing aging effects in killer T-cells.

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Groundbreaking Ceremony for the new CCII Research Building

A groundbreaking ceremony was held on 9th May 2022 for the Bristol Myers Squibb Building, the new home for CCII, to be constructed in the south-eastern part of the medical school campus.

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EMBO Podcast with Professor Honjo

In a new EMBO podcast, Thiago Carvalho talks to Tasuku Honjo about the journey from cell death to cancer immunotherapy. 

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Immunology as the Ultimate System Biology

A new paper published in Nature demonstrates a surprising role for the neurotransmitter GABA in orchestrating complex interactions between various immune cells.

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