Center for Cancer Immunotherapy and Immunobiology

Research Divisions, Labs & Researchers
Research at CCII is organized into six divisions, three divisions focused on fundamental research and three divisions focused on clinical and applied research, supported by two focus areas in analytic research, a “Multi-Omics Platform” and an “Informatics Platform”. The “Department for Genomic Medicine” is dedicated to industry-academia joint research and to our plan to make the new research building into an ideal place for collaborations and joint research. An experimental animal facility in the basement of the building will be available to all scientists at CCII and Kyoto University.

Highlights

Research Divisions, LabsProfessors
Department of Immunology and Genomic MedicineProf. Tasuku Honjo, Associate Prof. Nasim Begum, Associate Prof. Maki Kobayashi, Prof. Kenji Chamoto, Senior Lecturer Tomonori Yaguchi
Division of Integrated High-Order Regulatory SystemsProf. Sidonia Fagarasan, Senior Lecturer Masaki Tajima
Division of Cancer Immune Multicellular System RegulationProf. Hiroyoshi Nishikawa
Division of Clinical Immunology and Cancer ImmunotherapyAssociate Prof. Kosaku Murakami, Associate Prof. Hirotake Tsukamoto
Division of Cancer ImmunotherapyAssociate Prof. Ken Takahashi
Division of Clinical Pharmacology and Cancer ImmunotherapyAssociate Prof. Osamu Kikuchi
Multi-Omics PlatformAssociate Prof. Yuki Sugiura, Assistant Prof. Yuta Matsuoka
Informatics PlatformAssociate Prof. Kei Iida
Specially Appointed ProfessorsSpecially Appointed Prof. Masatoshi Hagiwara
Visiting Professors Associate Prof. J.B. Brown, Prof. Akio Ohta, Associate Prof. Kazuhiro Sonomura

Research Divisions, Labs & Researchers

Department of Immunology and Genomic Medicine

Our laboratory was the global pioneer in advocating PD-1 antibody-based cancer immunotherapy. Achieving a better understanding of the fundamental biology behind checkpoint inhibitors in human cancer models will help us to build better therapy regimes and enhance the efficiency and effectivity of cancer immunotherapy.

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Division of Integrated High-Order Regulatory Systems

Our goal is to build the basic tools for future immune system intervention in cancer and other diseases through research on immune system interactions in health and disease, using advanced proteomics and metabolomics tools.

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Division of Cancer Immune Multicellular System Regulation

We are developing unique analytical methods for studying the tumor microenvironment to comprehensively analyze interactions between the immune system and cancer cells. By establishing the concept that genetic abnormalities in cancer cells directly affect immune responses, we are pioneering a new field in tumor biology.

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Division of Clinical Immunology and Cancer Immunotherapy

We use immune adverse events in cancer immunotherapy together with bio-makers as model systems to better understand and predict the likelihood of success as well as risk factors of cancer immunotherapy in various types of cancer.

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Division of Cancer Immunotherapy

Our goal is to develop next generation cancer immunotherapies that enhance the efficacy of PD-1 blockade. We will maximize immune activation at tumor sites using a two sided approach, i.e. unique innate immunity-activating adjuvant and enhanced tumor destruction. 

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Division of Clinical Pharmacology and Cancer Immunotherapy

We are at the forefront of pioneering research and development in new molecular targeted therapies and immunotherapies that focus on the vulnerabilities arising from genetic alterations in cancer cells. Our mission is to develop effective and safe treatments tailored to individual patients.

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Multi-Omics Platform

Together with our collaborators at Kyoto University and in industry, we have been building a powerful new multi-omics platform to accelerate research into interactions between cancer and the immune system. This platform is available to all scientists at CCII and Kyoto University.

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Informatics Platform

Our platform advances and supports cancer immunology research by conducting in-silico analysis of quantitative data obtained from various devices, including high-throughput sequencers.

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Specially Appointed Professors

CCII is hosting scientists from Kyoto University, other national research institutions, industry or overseas research organizations with access to CCII’s special facilities and collaborative space.

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Visiting Researchers

Our goal at CCII is to work closely with organizations in academia and industry in Japan and abroad. Already today, CCII is hosting numerous of scientists from industry or overseas research organizations in visiting positions. CCII’s new research building is providing special facilities for visiting scientists.

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