CCII 京都大学大学院医学研究科附属 がん免疫総合研究センター

  1. Home
  2. 研究
  3. 研究部門、ラボ & 研究者
  4. がん免疫多細胞システム制御部門　
  5. セオ　ウセオク 准教授

セオ・ウセオク 准教授
がん免疫多細胞システム制御部門

学歴

  • 2002: University of Calgary, 修士（理学）
  • 2008: University of British Columbia, 博士（医学）

職歴

  • 2008-2009: University of British Columbia, Biomedical Research Centre, 研究員
  • 2009-2019: 理化学研究所, 生命医科学研究センター, 研究員
  • 2019-2024: 名古屋大学大学院・医学部研究科, 分子細胞免疫学, 特任准教授
  • 2023-2024: 名古屋大学・高等研究院医学部研究科, 若手新分野創成研究ユニット, 研究代表者（兼任）
  • 2025-現在: 京都大学大学院医学研究科附属がん免疫総合研究センター がん免疫多細胞システム制御部門 准教授

研究内容

所属学会

Selected Publications

Original Articles

1. Hung CJ, Tsai C-T, Rahaman SM, Yamanaka A, Seo W, Yokoyama T, Sakamoto M, Ono D. Neuropeptidergic input from the lateral hypothalamus to the suprachiasmatic nucleus alters the circadian period in mice. The Journal of Neuroscience, 2024. e0351242024-e0351242024.

2. Nomura A, Kobayashi T, Seo W, Ohno-Oishi M, Kakugawa K, Muroi S, Yoshida H, Endo, T A. Moro K, Taniuchi, I. Identification of a novel enhancer essential for Satb1expression in TH2 cells and activated ILC2s. Life Science Alliance. 2023. DOI: 10.26508/lsa.202301897.

3. Seo W, Shimizu K, Kojo S, Okeke A, Kohwi-Shigematsu T, Fujii S-I, Taniuchi I. Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity. Nat. Commun., 2020, 11 (1), 1562.

4. Kojo S, Ohno-Oishi M, Wada H, Nieke S, Seo W, Muroi S, Taniuchi I. Constitutive CD8 expression drives innate CD8+ T-cell differentiation via induction of iNKT2 cells. LSA, 2020, 3 (2).

5. Tenno M, Wong A, Ikegaya M, Miyauchi E, Seo W, See P, Kato T, Taida T, Oishi-Ohno M, Ohno H, Yoshida H, Ginhoux F, Taniuchi I. Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells. LSA, 2019, 3 (1).

6. Kojo S, Tanaka H, Endo TA, Muroi S, Liu Y, Seo W, Tenno M, Kakugawa K, Naoe Y, Nair K, Moro K, Katsuragi Y, Kanai A, Inaba T, Egawa T, Venkatesh B, Minoda A, Kominami R, Taniuchi I. Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes. Nat. Commun., 2017, 8 (1), 702.

7. Kakugawa K, Kojo S, Tanaka H, Seo W, Endo T, Katagawa Y, Muroi S, Tenno M, Yasmine N, Kohwi Y, Sakaguchi S, Kowhi-Shigematsu T, Taniuchi I. Essential Roles of SATB1 in Specifying T Lymphocyte Subsets. Cell Reports, 2017, 19 (6), 1176-1188.

8. Seo W, Muroi S, Akiyama K, Taniuchi I. Distinct requirement of Runx complexes for TCRβ enhancer activation at distinct developmental stages. Sci. Rep., 2017, 7, 41351.

9. Tanaka H, Naito T, Muroi S, Seo W, Chihara R, Miyamoto C, Kominami R, Taniuchi I. Epigenetic Thpok silencing limits the time window to choose CD4+ helper-lineage fate in the thymus. EMBO J., 2013, 32 (8), 1183-1194.

10. Seo W, Ikawa T, Kawamoto H. and Taniuchi I. Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1. J. Exp. Med., 2012, 209 (7), 1255-1262.

Review Articles

1. Seo W, Nomura A, Taniuchi I. The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity. Cells, 2022, 11 (19), 3116.

2. Seo W, Jerin C, Nishikawa H. Transcriptional regulatory network for the establishment of CD8 + T cell exhaustion. Exp. Mol. Med., 2021, 53 (2), 202-209.

3. Seo W & Taniuchi I. The Roles of RUNX Family Proteins in Development of Immune Cells. Mol. Cells, 2020, 43 (2), 107-113.

4. Seo W & Taniuchi I. Too much can be as bad as too little. Nat. Immunol., 2019, 20, 1262-1264.

5. Seo W & Taniuchi I. Regulation of hematopoiesis and immune responses by long noncoding RNAs. Int. Immunol., 2017, 29 (4), 165-172.

WordPress Lightbox